BIOMEC Biomechanical Engineering Lab
B2SLab is a multidisciplinary laboratory dedicated to data-driven biomedical research. Its mission is to advance healthcare through innovation, developing cutting-edge technologies that bridge the gap between data science and medical applications, improving patient outcomes and understanding complex biological systems. The group focuses on creating trustworthy, AI-based solutions to complex biomedical challenges, while also deepening our understanding of biological phenomena using computational modelling techniques, machine learning and statistics.

Research Areas
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Study of how the body moves, using motion capture and force analysis to better understand movement patterns in healthy and impaired individuals.
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Development of computational models that simulate how muscles, bones, and nerves work together, helping to optimize rehabilitation strategies and assistive device design.
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Design and testing of wearable sensors and devices that support motor recovery, track mobility progress, and enable continuous monitoring in real-life settings.
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Evaluation of how people interact physically and functionally with assistive technologies (e.g., exoskeletons), to ensure safety, comfort, and effectiveness.
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Design and implementation of clinical studies to assess the real-world impact, usability, and benefits of novel rehabilitation tools and medical devices.
Services Offered
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→ Biomechanical analysis and testing: motion capture, EMG, force plate, and pressure measurements to evaluate human movement.
→ Simulation and predictive modeling: development of neuromusculoskeletal models and in silico simulations to optimize assistive devices and rehabilitation strategies.
→ AI model biases assessment and auditing.
→ Bioinformatics Tools Development.
→ Creation and cocreation of software for omics data analysis.
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→ Prototyping and device development: design, fabrication, and testing of wearable and robotic rehabilitation technologies using the lab’s mechatronic workshop.
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→ Clinical validation and trials: design and execution of clinical studies to assess safety, performance, and usability of medical technologies in real-world settings.
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→ R&D collaboration and consulting: scientific and technical support for industrial innovation projects, including joint grant applications and technology co-development.
Featured Projects

TAILOR – Training the next generation of researchers in rehab robotics
European MSCA doctoral network focused on bringing robotic neurorehabilitation into clinical practice. TAILOR develops AI-driven controllers that adapt in real time to the patient’s motor status, improving therapy intensity, variability, and engagement. The project also promotes advanced training for researchers in personalized, intelligent rehab technologies.<br />
ArmTracker – Wearable system to monitor arm function in neuromuscular diseases
Development of a smart wearable for real-life monitoring of upper limb movement in patients with Duchenne muscular dystrophy and spinal muscular atrophy. It captures daily motion data (range, distribution, acceleration) and applies machine learning to generate objective biomarkers that support treatment decisions and track outcomes.

ABLE DailyExo – Smart exoskeletons for everyday use
In collaboration with Able Human Motion, this project designs and tests a new generation of lightweight, affordable robotic exoskeletons for home and community use. The goal is to help people with mobility impairments regain autonomy in daily tasks like walking or climbing stairs, overcoming the limits of current clinical-only devices.

TAILOR – Training the next generation of researchers in rehab robotics
European MSCA doctoral network focused on bringing robotic neurorehabilitation into clinical practice. TAILOR develops AI-driven controllers that adapt in real time to the patient’s motor status, improving therapy intensity, variability, and engagement. The project also promotes advanced training for researchers in personalized, intelligent rehab technologies.<br />
ArmTracker – Wearable system to monitor arm function in neuromuscular diseases
Development of a smart wearable for real-life monitoring of upper limb movement in patients with Duchenne muscular dystrophy and spinal muscular atrophy. It captures daily motion data (range, distribution, acceleration) and applies machine learning to generate objective biomarkers that support treatment decisions and track outcomes.

ABLE DailyExo – Smart exoskeletons for everyday use
In collaboration with Able Human Motion, this project designs and tests a new generation of lightweight, affordable robotic exoskeletons for home and community use. The goal is to help people with mobility impairments regain autonomy in daily tasks like walking or climbing stairs, overcoming the limits of current clinical-only devices.
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